Urolithin A vs. CoQ10: Which One Does Your Midlife Body Really Need?
Let’s Get Real for a Second...
You know that feeling when your body just isn’t keeping up with your life anymore? You’re doing all the “right” things—eating well (most of the time), moving your body, getting sleep when you can—but you still feel wiped out by 3 PM.
Your brain? Foggy.
Your muscles? Sluggish.
Your energy? Nonexistent.
So, naturally, you start Googling—"best supplements for energy and aging"—and suddenly, you’re drowning in ads for Urolithin A and CoQ10. They both sound promising, but which one do you actually need?
Let’s break it down. No fluff. No gimmicks. Just real, practical advice that fits into your very full life.
Urolithin A: The Mitochondria Booster
What It Does
Clears out old, damaged mitochondria (mitophagy)
Helps your body produce more energy at a cellular level
Supports muscle strength and endurance
May improve brain health and longevity
Who It’s For
Struggling with muscle fatigue and slow recovery
Feeling like your energy is running on fumes
Looking to support healthy aging at a deep, cellular level
How to Take It
Dose: 500–1000 mg per day
Best Time: Morning with food for better absorption.
Best Urolithin A Supplements
Mitopure® by Timeline Nutrition (clinically studied, highly bioavailable)
Healthycell Mitochondria+ (a liquid format that’s easy to absorb)
Pomi-T® (polyphenols that support natural Urolithin A production)
CoQ10: The Energy Spark Plug
What It Does
Powers up your mitochondria to produce ATP (cellular energy)
Protects your cells from oxidative stress and inflammation
Supports heart health (especially in perimenopause and menopause)
Helps counteract statin-related muscle pain
Who It’s For
Feeling exhausted and drained all the time
Taking statins (cholesterol meds) and experiencing muscle pain
Wanting brain and cardiovascular support
How to Take It
Dose: 100–300 mg per day
Best Time: With a meal that contains healthy fat (like avocado or nuts) for better absorption.
Best CoQ10 Supplements
Qunol Ultra CoQ10 Ubiquinol (highly absorbable)
Pure Encapsulations CoQ10 200 mg (trusted quality)
Life Extension Super Ubiquinol CoQ10 (includes PQQ for extra mitochondrial support)
So… Which One Should You Take?
Here’s the deal: Urolithin A and CoQ10 actually work well together.
✔ Urolithin A helps clean out and renew your mitochondria.
✔ CoQ10 helps those mitochondria produce more energy efficiently.
If you’re deep in perimenopause/menopause and struggling with fatigue, muscle weakness, and brain fog, taking both might be the ultimate power combo.
How to Add These Supplements to Your Daily Routine
Let’s keep this realistic and doable—no complicated supplement regimens here.
Morning (Start the Day Right)
With Breakfast: Take Urolithin A (500–1000 mg) with a meal that has some healthy fat (like eggs, nuts, or yogurt). This helps with absorption and gives you that early energy boost.
Pro Tip: If you drink a morning smoothie, add a pomegranate extract to boost your natural Urolithin A production.
Midday (Keep the Energy Going)
With Lunch: Take CoQ10 (100–300 mg) with food for better absorption.
Bonus Tip: If you’re working out in the afternoon, CoQ10 can help with endurance and recovery.
Evening (Optional for Extra Support)
If you take statins: Consider taking CoQ10 at night to help counteract muscle pain while you sleep.
If you feel drained at the end of the day: A split dose of Urolithin A (500 mg in the morning, 500 mg at night) might help keep your energy steady.
Final Thoughts: Small Changes, Big Impact
The reality is—your body is changing, and that’s okay.
You don’t need a 12-step supplement routine or an intense lifestyle overhaul to feel better.
Want to improve energy, muscle strength, and longevity? Try Urolithin A.
Need a boost in cellular energy and heart health? CoQ10 is your go-to.
Want to feel your best? Consider taking both—they work together beautifully.
The most important thing? Listen to your body. Take what serves you, and leave the rest.
Over to You…
Have you tried Urolithin A or CoQ10? What was your experience?
Need help figuring out which supplements are best for YOU? Drop a comment below—I’d love to chat! You can also create a client profile through my Fullscript dispensary to receive a discount on all your supplements as well as recommendations from me!
Want more practical, no-BS midlife health advice? Join my Women Mastering Midlife community—because you deserve simple, sustainable solutions that fit your life.